The age-related characteristics of lymphoid tissue in the intestinal wall of bobak marmot. Osobennosti limfoidnoïtkani stenki kichetchika ou stepnogo sourka vvozrastnom aspekte. [Caractéristiques liées à l’âge du tissu lymphoïde de la paroi intestinale de la marmotte bobak].

Résumé

Lymphoid tissue of the intestinal wall is an integral part of the single immune system of mucosa (SISM) and is the first to provide immune defense to the organism when contacting with chymus. During the work there was studied lyrnphoid tissue of the intestinal wall (Peyer's patches and single lymphoidnodules) in an herbivorous representative of the Order Rodents - steppe marmot - aged 1.5 years and 8-10 years. This study showed that a total area of intestines in 1.5 year old animals was 944.28 ? 77.97 cm2 on the average. This is 44.6 % less than in animals aged 8-10 years (1365.89 ? 69.34 cm2). Lyrnphoid tissue of the intestinal wall is represented by single lymphoid nodules, which appear as lymphoid patches. In the 1.5 year old marmots their total number was 84.5 ? 3.53, in older marmots -78.2 ? 7.88. A total number of lyrnphoid nodules in lymphoid patches decrease with the age from 1767.12? 114.68 to 1079.88 ? 106.44. A majority of lymphoid patches of the small intestine is located in the wall of jejunum. The animals of different ages have almost the same number of the lyrnphoid patches - 16.45, on the average. Despite it, number of lymphoid nodules in the lymphoid patches in the small intestine of marmots aged 1.5 year and those aged 8-10 years, was considerably different. ln young animals an average number of lymphoid nodules in one lymphoid patch made up 34.47 ? 3.25, while that in the marmots of older age made up 20.17 ?. 77. A maximum number of Peyer's patches in the large intestine were detected in crassum. In the 1.5 year old animals and mature animals it was practically at the same level: 44.33 ? 4.0 and 41.00 ? 5.17, respectively. Number of lyrnphoid nodules in lymphoid patches of young animals was, for certain, 65 percent more compared with 8-10 year old marmots and made up 742.75 ? 65.54 and 486.50 ? 60.28, respectively. Therefore, decrease in the quantity of lyrnphoid nodules is observed, though an amount of lyrnphoid patches remaining stable.